Certified Hyperbaric Technologist Practice Test

What is the role of HBO in treating reperfusion injury?

1. To destroy bacteria in tissues

2. To decrease pain sensations

3. To diminish neutrophil damage, oxygenate hypoxic tissues, and reduce edema

4. To enhance blood circulation

The correct answer is: To diminish neutrophil damage, oxygenate hypoxic tissues, and reduce edema

The role of hyperbaric oxygen (HBO) therapy in treating reperfusion injury primarily involves its ability to diminish neutrophil damage, oxygenate hypoxic tissues, and reduce edema. Reperfusion injury occurs when blood supply returns to tissue after a period of ischemia (lack of oxygen), which can lead to an inflammatory response and additional damage due to oxygen radicals and neutrophil activation. By administering oxygen at high pressure, HBO therapy increases the amount of oxygen dissolved in the plasma, allowing for more effective delivery to previously ischemic tissues. This oxygenation helps reduce hypoxia, thereby enhancing cellular metabolism and survival in affected areas. Additionally, the hyperbaric environment can help modulate inflammation by reducing the permeability of the blood vessels, which aids in minimizing edema. The reduction of neutrophil damage occurs because HBO can help limit the oxidative stress associated with reperfusion injury, promoting a more favorable healing environment. While other options mention beneficial effects of various treatments, they do not specifically address the multifaceted action of HBO in the context of reperfusion injury, where its role as an oxygen delivery system and an anti-inflammatory agent is crucial.